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Characterization of Early EDEM1 Protein Maturation Events and Their Functional Implications

The endoplasmic reticulum (ER) quality control factor EDEM1 associates with a number of ER proteins and ER-associated degradation (ERAD) substrates; however, an understanding of its role in ERAD is unclear. The early maturation events for EDEM1 including signal sequence cleavage and glycosylation we...

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Detalhes bibliográficos
Main Authors: Tamura, Taku, Cormier, James H., Hebert, Daniel N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137065/
https://ncbi.nlm.nih.gov/pubmed/21632540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.243998
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