Functional Involvement of Dual Specificity Phosphatase 16 (DUSP16), a c-Jun N-terminal Kinase-specific Phosphatase, in the Regulation of T Helper Cell Differentiation

Naïve CD4(+) T helper (Th) cells differentiate into distinct subsets of effector cells (Th1, Th2, Th17, and induced regulatory T cells (iTreg)) expressing different sets of cytokines upon encounter with presented foreign antigens. It has been well established that Th1/Th2 balance is critical for the...

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Main Authors: Musikacharoen, Tipayaratn, Bandow, Kenjiro, Kakimoto, Kyoko, Kusuyama, Joji, Onishi, Tomokazu, Yoshikai, Yasunobu, Matsuguchi, Tetsuya
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137064/
https://ncbi.nlm.nih.gov/pubmed/21613215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.245019
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