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Inactivation of tesA Reduces Cell Wall Lipid Production and Increases Drug Susceptibility in Mycobacteria

Phthiocerol dimycocerosates (PDIMs) and phenolic glycolipids (PGLs) are structurally related lipids noncovalently bound to the outer cell wall layer of Mycobacterium tuberculosis, Mycobacterium leprae, and several opportunistic mycobacterial human pathogens. PDIMs and PGLs are important effectors of...

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Detalhes bibliográficos
Main Authors: Chavadi, Sivagami Sundaram, Edupuganti, Uthamaphani R., Vergnolle, Olivia, Fatima, Itrat, Singh, Shaneen M., Soll, Clifford E., Quadri, Luis E. N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137037/
https://ncbi.nlm.nih.gov/pubmed/21592957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.247601
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