Inactivation of tesA Reduces Cell Wall Lipid Production and Increases Drug Susceptibility in Mycobacteria

Phthiocerol dimycocerosates (PDIMs) and phenolic glycolipids (PGLs) are structurally related lipids noncovalently bound to the outer cell wall layer of Mycobacterium tuberculosis, Mycobacterium leprae, and several opportunistic mycobacterial human pathogens. PDIMs and PGLs are important effectors of...

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Autores principales: Chavadi, Sivagami Sundaram, Edupuganti, Uthamaphani R., Vergnolle, Olivia, Fatima, Itrat, Singh, Shaneen M., Soll, Clifford E., Quadri, Luis E. N.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Microbiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137037/
https://ncbi.nlm.nih.gov/pubmed/21592957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.247601
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