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Inactivation of tesA Reduces Cell Wall Lipid Production and Increases Drug Susceptibility in Mycobacteria

Phthiocerol dimycocerosates (PDIMs) and phenolic glycolipids (PGLs) are structurally related lipids noncovalently bound to the outer cell wall layer of Mycobacterium tuberculosis, Mycobacterium leprae, and several opportunistic mycobacterial human pathogens. PDIMs and PGLs are important effectors of...

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Bibliografiske detaljer
Main Authors: Chavadi, Sivagami Sundaram, Edupuganti, Uthamaphani R., Vergnolle, Olivia, Fatima, Itrat, Singh, Shaneen M., Soll, Clifford E., Quadri, Luis E. N.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137037/
https://ncbi.nlm.nih.gov/pubmed/21592957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.247601
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