Inactivation of tesA Reduces Cell Wall Lipid Production and Increases Drug Susceptibility in Mycobacteria

Phthiocerol dimycocerosates (PDIMs) and phenolic glycolipids (PGLs) are structurally related lipids noncovalently bound to the outer cell wall layer of Mycobacterium tuberculosis, Mycobacterium leprae, and several opportunistic mycobacterial human pathogens. PDIMs and PGLs are important effectors of...

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Autors principals: Chavadi, Sivagami Sundaram, Edupuganti, Uthamaphani R., Vergnolle, Olivia, Fatima, Itrat, Singh, Shaneen M., Soll, Clifford E., Quadri, Luis E. N.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
Matèries:
Microbiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137037/
https://ncbi.nlm.nih.gov/pubmed/21592957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.247601
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