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Plk2 Raps up Ras to subdue synapses

We recently identified the activity-inducible protein kinase Plk2 as a novel overseer of the balance between Ras and Rap small GTPases. Plk2 achieves a profound level of regulatory control by interacting with and phosphorylating at least four Ras and Rap guanine nucleotide exchange factors (GEFs) an...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lee, Kea Joo, Hoe, Hyang-Sook, Pak, Daniel TS
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136947/
https://ncbi.nlm.nih.gov/pubmed/21776418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.2.3.16454
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