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The regulation of osteoclast function and bone resorption by small GTPases

Osteoclasts are multinucleated cells that are responsible for resorption of bone, and increased activity of these cells is associated with several common bone diseases, including postmenopausal osteoporosis. Upon adhesion to bone, osteoclasts become polarized and reorganise their cytoskeleton and me...

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Bibliografiske detaljer
Main Authors: Itzstein, Cecile, Coxon, Fraser P, Rogers, Michael J
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136942/
https://ncbi.nlm.nih.gov/pubmed/21776413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.2.3.16453
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