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The regulation of osteoclast function and bone resorption by small GTPases

Osteoclasts are multinucleated cells that are responsible for resorption of bone, and increased activity of these cells is associated with several common bone diseases, including postmenopausal osteoporosis. Upon adhesion to bone, osteoclasts become polarized and reorganise their cytoskeleton and me...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Itzstein, Cecile, Coxon, Fraser P, Rogers, Michael J
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136942/
https://ncbi.nlm.nih.gov/pubmed/21776413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.2.3.16453
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