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Direct Measurements of Torque During Holliday Junction Migration

DNA experiences torsional stress resulting from the activities of motor enzymes and bound proteins. The mechanisms by which this torsional stress is dissipated to maintain DNA structural integrity are not fully known. Here, we show that a Holliday junction can limit torsion by coupling rotation to t...

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Detalhes bibliográficos
Main Authors: Forth, Scott, Deufel, Christopher, Patel, Smita S., Wang, Michelle D.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136780/
https://ncbi.nlm.nih.gov/pubmed/21767475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.05.066
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