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Direct Measurements of Torque During Holliday Junction Migration

DNA experiences torsional stress resulting from the activities of motor enzymes and bound proteins. The mechanisms by which this torsional stress is dissipated to maintain DNA structural integrity are not fully known. Here, we show that a Holliday junction can limit torsion by coupling rotation to t...

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Hlavní autoři: Forth, Scott, Deufel, Christopher, Patel, Smita S., Wang, Michelle D.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136780/
https://ncbi.nlm.nih.gov/pubmed/21767475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.05.066
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