Osteogenesis Imperfecta Model Peptides: Incorporation of Residues Replacing Gly within a Triple Helix Achieved by Renucleation and Local Flexibility

Missense mutations, which replace one Gly with a larger residue in the repeating sequence of the type I collagen triple helix, lead to the hereditary bone disorder osteogenesis imperfecta (OI). Previous studies suggest that these mutations may interfere with triple-helix folding. NMR was used to inv...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Xiao, Jianxi, Madhan, Balaraman, Li, Yingjie, Brodsky, Barbara, Baum, Jean
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The Biophysical Society 2011
विषय:
Protein
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136760/
https://ncbi.nlm.nih.gov/pubmed/21767498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.06.017
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