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Granzyme B cleavage of autoantigens in autoimmunity

The systemic autoimmune diseases are a complex group of disorders characterized by elaboration of high titer autoantibodies and immune-mediated damage of tissues. Two striking features of autoimmune rheumatic diseases are their self-sustaining nature and capacity for auto-amplification, exemplified...

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Bibliografiske detaljer
Main Authors: Darrah, Erika, Rosen, Antony
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136751/
https://ncbi.nlm.nih.gov/pubmed/20075942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2009.197
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