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Normal-Mode Refinement of Anisotropic Thermal Parameters for Potassium Channel KcsA at 3.2 Å Crystallographic Resolution

We report a normal-mode method for anisotropic refinement of membrane-protein structures, based on a hypothesis that the global near-native-state disordering of membrane proteins in crystals follows low-frequency normal modes. Thus, a small set of modes is sufficient to represent the anisotropic the...

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Autori principali: Chen, Xiaorui, Poon, Billy K., Dousis, Athanasios, Wang, Qinghua, Ma, Jianpeng
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136661/
https://ncbi.nlm.nih.gov/pubmed/17698000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2007.06.012
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