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Ultrasensitive Identification of Localization Variants of Modified Peptides Using Ion Mobility Spectrometry

Localization of the modification sites on peptides is challenging, particularly when multiple modifications or mixtures of localization isomers (variants) are involved. Such variants commonly coelute in liquid chromatography and may be undistinguishable in tandem mass spectrometry (MS/MS) for lack o...

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Detalhes bibliográficos
Main Authors: Ibrahim, Yehia M., Shvartsburg, Alexandre A., Smith, Richard D., Belov, Mikhail E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136632/
https://ncbi.nlm.nih.gov/pubmed/21692493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac200719n
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