FUNCTIONAL POLYMORPHISMS OF BASE EXCISION REPAIR GENES XRCC1 AND APEX1 PREDICT RISK OF RADIATION PNEUMONITIS IN PATIENTS WITH NON-SMALL CELL LUNG CANCER TREATED WITH DEFINITIVE RADIATION THERAPY

PURPOSE: To explore if functional single nucleotide polymorphisms (SNPs) of base-excision repair genes are predictors of radiation treatment-related pneumonitis (RP), we investigated associations between functional SNPs of ADPRT, APEX1, and XRCC1 and RP development. METHODS AND MATERIALS: We genotyp...

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Autori principali: YIN, MING, LIAO, ZHONGXING, LIU, ZHENSHENG, WANG, LI-E, GOEMZ, DANIEL, KOMAKI, RITSUKO, WEI, QINGYI
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136565/
https://ncbi.nlm.nih.gov/pubmed/21420246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2010.11.079
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