Structural and Functional Profiling of the Human Histone Methyltransferase SMYD3

The SET and MYND Domain (SMYD) proteins comprise a unique family of multi-domain SET histone methyltransferases that are implicated in human cancer progression. Here we report an analysis of the crystal structure of the full length human SMYD3 in a complex with an analog of the S-adenosyl methionine...

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Autors principals: Foreman, Kenneth W., Brown, Mark, Park, Frances, Emtage, Spencer, Harriss, June, Das, Chhaya, Zhu, Li, Crew, Andy, Arnold, Lee, Shaaban, Salam, Tucker, Philip
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136521/
https://ncbi.nlm.nih.gov/pubmed/21779408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022290
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