The Role of IL-15 Deficiency in the Pathogenesis of Virus-Induced Asthma Exacerbations

Rhinovirus infections are the major cause of asthma exacerbations. We hypothesised that IL-15, a cytokine implicated in innate and acquired antiviral immunity, may be deficient in asthma and important in the pathogenesis of asthma exacerbations. We investigated regulation of IL-15 induction by rhino...

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Detalhes bibliográficos
Main Authors: Laza-Stanca, Vasile, Message, Simon D., Edwards, Michael R., Parker, Hayley L., Zdrenghea, Mihnea T., Kebadze, Tatiana, Kon, Onn M., Mallia, Patrick, Stanciu, Luminita A., Johnston, Sebastian L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136447/
https://ncbi.nlm.nih.gov/pubmed/21779162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002114
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