Rhinovirus-induced lower respiratory illness is increased in asthma and related to virus load and Th1/2 cytokine and IL-10 production

Acute exacerbations are the major cause of asthma morbidity, mortality, and health-care costs and are difficult to treat and prevent. The majority of asthma exacerbations are associated with rhinovirus (RV) infection, but evidence supporting a causal relationship is weak and mechanisms are poorly un...

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Bibliografiske detaljer
Main Authors: Message, Simon D., Laza-Stanca, Vasile, Mallia, Patrick, Parker, Hayley L., Zhu, Jie, Kebadze, Tatiana, Contoli, Marco, Sanderson, Gwen, Kon, Onn M., Papi, Alberto, Jeffery, Peter K., Stanciu, Luminita A., Johnston, Sebastian L.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2008
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2528869/
https://ncbi.nlm.nih.gov/pubmed/18768794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0804181105
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