Sialylation and fucosylation of epidermal growth factor receptor suppress its dimerization and activation in lung cancer cells

Protein glycosylation is an important posttranslational process, which regulates protein folding and functional expression. Studies have shown that abnormal glycosylation in tumor cells affects cancer progression and malignancy. In the current study, we have identified sialylated proteins using an a...

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Autori principali: Liu, Ying-Chih, Yen, Hsin-Yung, Chen, Chien-Yu, Chen, Chein-Hung, Cheng, Ping-Fu, Juan, Yi-Hsiu, Chen, Chung-Hsuan, Khoo, Kay-Hooi, Yu, Chong-Jen, Yang, Pan-Chyr, Hsu, Tsui-Ling, Wong, Chi-Huey
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2011
Soggetti:
Physical Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136320/
https://ncbi.nlm.nih.gov/pubmed/21709263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107385108
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