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Sialylation and fucosylation of epidermal growth factor receptor suppress its dimerization and activation in lung cancer cells

Protein glycosylation is an important posttranslational process, which regulates protein folding and functional expression. Studies have shown that abnormal glycosylation in tumor cells affects cancer progression and malignancy. In the current study, we have identified sialylated proteins using an a...

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Detalhes bibliográficos
Main Authors: Liu, Ying-Chih, Yen, Hsin-Yung, Chen, Chien-Yu, Chen, Chein-Hung, Cheng, Ping-Fu, Juan, Yi-Hsiu, Chen, Chung-Hsuan, Khoo, Kay-Hooi, Yu, Chong-Jen, Yang, Pan-Chyr, Hsu, Tsui-Ling, Wong, Chi-Huey
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136320/
https://ncbi.nlm.nih.gov/pubmed/21709263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107385108
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