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Epidermal ablation of Dlx3 is linked to IL-17–associated skin inflammation
In an effort to understand the role of Distal-less 3 (Dlx3) in cutaneous biology and pathophysiology, we generated and characterized a mouse model with epidermal ablation of Dlx3. K14cre;Dlx3(Kin/f) mice exhibited epidermal hyperproliferation and abnormal differentiation of keratinocytes. Results fr...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3136280/ https://ncbi.nlm.nih.gov/pubmed/21709238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1019658108 |
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