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Myosin VIIa and sans localization at stereocilia upper tip-link density implicates these Usher syndrome proteins in mechanotransduction

In the most accepted model for hair cell mechanotransduction, a cluster of myosin motors located at the stereocilia upper tip-link density (UTLD) keeps the tip-link under tension at rest. Both myosin VIIa (MYO7A) and myosin 1c have been implicated in mechanotransduction based on functional studies....

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Détails bibliographiques
Auteurs principaux: Grati, M’hamed, Kachar, Bechara
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136276/
https://ncbi.nlm.nih.gov/pubmed/21709241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1104161108
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