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Regulation of stereocilia length by myosin XVa and whirlin depends on the actin-regulatory protein Eps8

Myosin XVa (MyoXVa) and its cargo whirlin are implicated in deafness and vestibular dysfunction and have been shown to localize at stereocilia tips and to be essential for the elongation of these actin protrusions [1–4]. Given that whirlin has no known actin-regulatory activity, it remains unclear h...

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Detalhes bibliográficos
Main Authors: Manor, Uri, Disanza, Andrea, Grati, M'Hamed, Andrade, Leonardo, Lin, Harrison, Di Fiore, Pier Paolo, Scita, Giorgio, Kachar, Bechara
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040242/
https://ncbi.nlm.nih.gov/pubmed/21236676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2010.12.046
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