Cargando...

Crystal Structure of Human Protein Tyrosine Phosphatase SHP-1 in the Open Conformation

SHP-1 belongs to the family of non-receptor protein tyrosine phosphatases (PTPs) and generally acts as a negative regulator in a variety of cellular signaling pathways. Previously the crystal structures of the tail-truncated SHP-1 and SHP-2 revealed an autoinhibitory conformation. To understand the...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Wang, Wei, Liu, Lijun, Song, Xi, Mo, Yi, Komma, Chandrasekhar, Bellamy, Henry D., Zhao, Zhizhuang Joe, Zhou, G. Wayne
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135737/
https://ncbi.nlm.nih.gov/pubmed/21465528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.23125
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!