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Heparin Induces Harmless Fibril Formation in Amyloidogenic W7FW14F Apomyoglobin and Amyloid Aggregation in Wild-Type Protein In Vitro

Glycosaminoglycans (GAGs) are frequently associated with amyloid deposits in most amyloid diseases, and there is evidence to support their active role in amyloid fibril formation. The purpose of this study was to obtain structural insight into GAG-protein interactions and to better elucidate the mol...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Vilasi, Silvia, Sarcina, Rosalba, Maritato, Rosa, De Simone, Antonella, Irace, Gaetano, Sirangelo, Ivana
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135624/
https://ncbi.nlm.nih.gov/pubmed/21779376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022076
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