Different metastasis promotive potency of small G-proteins RalA and RalB in in vivo hamster tumor model

BACKGROUND: Previously we have shown that oncogenic Ha-Ras stimulated in vivo metastasis through RalGEF-Ral signaling. RalA and RalB are highly homologous small G proteins belonging to Ras superfamily. They can be activated by Ras-RalGEF signaling pathway and influence cellular growth and survival,...

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Main Authors: Rybko, Vera A, Knizhnik, Anna V, Komelkov, Andrei V, Aushev, Vasily N, Trukhanova, Lyubov S, Tchevkina, Elena M
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2011
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Primary Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135494/
https://ncbi.nlm.nih.gov/pubmed/21714887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-11-22
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