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SOCS2 regulates T helper type 2 differentiation and the generation of type 2 allergic responses

The incidence of allergy and asthma in developed countries is on the increase and this trend looks likely to continue. CD4(+) T helper 2 (Th2) cells are major drivers of these diseases and their commitment is controlled by cytokines such as interleukin 4, which are in turn regulated by the suppresso...

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Hlavní autoři: Knosp, Camille A., Carroll, Helen P., Elliott, Joanne, Saunders, Sean P., Nel, Hendrik J., Amu, Sylvie, Pratt, Joanne C., Spence, Shaun, Doran, Emma, Cooke, Nicola, Jackson, Ruaidhri, Swift, Jonathan, Fitzgerald, Denise C., Heaney, Liam G., Fallon, Padraic G., Kissenpfennig, Adrien, Johnston, James A.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135359/
https://ncbi.nlm.nih.gov/pubmed/21646394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20101167
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