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Enhanced Subcortical Spreading Depression in Familial Hemiplegic Migraine Type 1 Mutant Mice
Familial hemiplegic migraine type 1, a monogenic migraine variant with aura, is linked to gain-of-function mutations in the CACNA1A gene encoding Ca(V)2.1 channels. The S218L mutation causes severe channel dysfunction, and paroxysmal migraine attacks can be accompanied by seizures, coma, and hemiple...
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| Main Authors: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Society for Neuroscience
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3135337/ https://ncbi.nlm.nih.gov/pubmed/21490217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5346-10.2011 |
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