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MK-STYX, a Catalytically Inactive Phosphatase Regulating Mitochondrially Dependent Apoptosis
Evasion of apoptosis is a significant problem affecting an array of cancers. In order to identify novel regulators of apoptosis, we performed an RNA interference (RNAi) screen against all kinases and phosphatases in the human genome. We identified MK-STYX (STYXL1), a catalytically inactive phosphata...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3135289/ https://ncbi.nlm.nih.gov/pubmed/21262771 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00788-10 |
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