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Selenium status highly-regulates selenoprotein mRNA levels for only a subset of the selenoproteins in the selenoproteome
Gpx (glutathione peroxidase)-1 enzyme activity and mRNA levels decrease dramatically in selenium (Se) deficiency, whereas other selenoproteins are less affected by Se deficiency. This hierarchy of Se regulation is not understood, but the position of the UGA selenocysteine codon is thought to play a...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3135282/ https://ncbi.nlm.nih.gov/pubmed/19076066 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20080146 |
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