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Selenium status highly-regulates selenoprotein mRNA levels for only a subset of the selenoproteins in the selenoproteome

Gpx (glutathione peroxidase)-1 enzyme activity and mRNA levels decrease dramatically in selenium (Se) deficiency, whereas other selenoproteins are less affected by Se deficiency. This hierarchy of Se regulation is not understood, but the position of the UGA selenocysteine codon is thought to play a...

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Autors principals: SUNDE, Roger A., RAINES, Anna M., BARNES, Kimberly M., EVENSON, Jacqueline K.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135282/
https://ncbi.nlm.nih.gov/pubmed/19076066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20080146
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