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A racemic formal total synthesis of clavukerin A using gold(I)-catalyzed cycloisomerization of 3-methoxy-1,6-enynes as the key strategy

An efficient formal total synthesis of (±)-clavukerin A was accomplished via a gold-catalyzed cycloisomerization of a 3-methoxy-1,6-enyne 5 as the key strategy followed by Rh-catalyzed stereoselective hydrogenation of the cycloheptenone 4.

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Autori principali: Cheong, Jae Youp, Rhee, Young Ho
Natura: Artigo
Lingua:Inglês
Pubblicazione: Beilstein-Institut 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135252/
https://ncbi.nlm.nih.gov/pubmed/21804869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.7.84
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