Isolation of orally attenuated Salmonella typhimurium following TnphoA mutagenesis.

One hundred fifty Tn5 IS50L::phoA (TnphoA) mutants of a mouse-virulent, nalidixic acid-resistant (Nalr), prototrophic Salmonella typhimurium strain, C5 Nalr, were isolated. None of the mutants were auxotrophs. Groups of 8 to 10 BALB/c mice were infected orally with each of 95 mutants with a dose equ...

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Detalles Bibliográficos

Publicado en:	Infect Immun
Autores principales:	Miller, I, Maskell, D, Hormaeche, C, Johnson, K, Pickard, D, Dougan, G
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1989
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC313522/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2668186/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.57.9.2758-2763.1989
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