An unusual pagC::TnphoA mutation leads to an invasion- and virulence-defective phenotype in Salmonellae.

Two phenotypes believed to contribute to the pathogenesis of Salmonella infections are macrophage survival and invasion of epithelial cells. It was recently observed that the Salmonella macrophage survival factor PagC has significant amino acid similarity to the Yersinia invasion factor Ail. This ob...

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Détails bibliographiques
Publié dans:Infect Immun
Auteurs principaux: Miller, V L, Beer, K B, Loomis, W P, Olson, J A, Miller, S I
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1992
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257388/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1323535/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.9.3763-3770.1992
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