An unusual pagC::TnphoA mutation leads to an invasion- and virulence-defective phenotype in Salmonellae.

Two phenotypes believed to contribute to the pathogenesis of Salmonella infections are macrophage survival and invasion of epithelial cells. It was recently observed that the Salmonella macrophage survival factor PagC has significant amino acid similarity to the Yersinia invasion factor Ail. This ob...

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Pubblicato in:	Infect Immun
Autori principali:	Miller, V L, Beer, K B, Loomis, W P, Olson, J A, Miller, S I
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1992
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257388/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1323535/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.9.3763-3770.1992
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