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Homoallylic amines by reductive inter- and intramolecular coupling of allenes and nitriles

The one-pot hydrozirconation of allenes and nitriles followed by an in situ transmetalation of the allylzirconocene with dimethylzinc or zinc chloride provides functionalized homoallylic amines. An intramolecular version of this process leads to 3-aminotetrahydrofurans and 3-aminotetrahydropyrans.

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Hlavní autoři: Wipf, Peter, Manojlovic, Marija D
Médium: Artigo
Jazyk:Inglês
Vydáno: Beilstein-Institut 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135093/
https://ncbi.nlm.nih.gov/pubmed/21804878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.7.94
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