Development of Lipid-Based Nanoparticles for Enhancing the Oral Bioavailability of Paclitaxel

The current research work investigates the potential of solid lipid nanoparticles (SLNs) in improving the oral bioavailability of paclitaxel. Paclitaxel-loaded SLNs (PTX-SLNs) were prepared by modified solvent injection method using stearylamine as lipid, soya lecithin and poloxamer 188 as emulsifie...

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Main Authors: Pandita, Deepti, Ahuja, Alka, Lather, Viney, Benjamin, Biju, Dutta, Tathagata, Velpandian, Thirumurthy, Khar, Roop Krishen
Format: Artigo
Jezik:Inglês
Izdano: Springer US 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3134658/
https://ncbi.nlm.nih.gov/pubmed/21637945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-011-9636-8
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