Phosphorylation of histone H3 serine 28 modulates RNA polymerase III-dependent transcription

Deregulation of RNA polymerase III (Pol III) transcription enhances cellular tRNAs and 5S rRNA production, leading to an increase in translational capacity to promote cell proliferation, transformation and tumor formation. Phosphorylation of histone H3 (H3ph) is induced by tumor promoters (EGF, UV a...

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Hauptverfasser: Zhang, Qingsong, Zhong, Qian, Evans, Austin G., Levy, Daniel, Zhong, Shuping
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3134635/
https://ncbi.nlm.nih.gov/pubmed/21460852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.105
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