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Phosphorylation of histone H3 serine 28 modulates RNA polymerase III-dependent transcription
Deregulation of RNA polymerase III (Pol III) transcription enhances cellular tRNAs and 5S rRNA production, leading to an increase in translational capacity to promote cell proliferation, transformation and tumor formation. Phosphorylation of histone H3 (H3ph) is induced by tumor promoters (EGF, UV a...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3134635/ https://ncbi.nlm.nih.gov/pubmed/21460852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.105 |
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