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Interaction networks of lithium and valproate molecular targets reveal a striking enrichment of apoptosis functional clusters and neurotrophin signaling

The overall neurobiological mechanisms by which lithium and valproate stabilize mood in bipolar disorder patients have yet to be fully defined. The therapeutic efficacy and dissimilar chemical structures of these medications suggest that they perturb both shared and disparate cellular processes. To...

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Detalhes bibliográficos
Main Authors: Gupta, Ajay, Schulze, Thomas G, Nagarajan, Vijayaraj, Akula, Nirmala, Corona, Winston, Jiang, Xue-ying, Hunter, Natasha, McMahon, Francis J, Detera-Wadleigh, Sevilla D
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3134562/
https://ncbi.nlm.nih.gov/pubmed/21383773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2011.9
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