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Recent Advances in p53 Research and Cancer Treatment

TP53, encoding p53, is one of the most famous tumor suppressor genes. The majority of human cancers demonstrate the inactivation of the p53 pathway. Mutant p53 not only, no longer, functions as a tumor suppressor but can also exert tumor-promoting effects. The basic function of p53 is to respond to...

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Autors principals: Suzuki, Kazufumi, Matsubara, Hisahiro
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3134396/
https://ncbi.nlm.nih.gov/pubmed/21765642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/978312
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