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Recent Advances in p53 Research and Cancer Treatment

TP53, encoding p53, is one of the most famous tumor suppressor genes. The majority of human cancers demonstrate the inactivation of the p53 pathway. Mutant p53 not only, no longer, functions as a tumor suppressor but can also exert tumor-promoting effects. The basic function of p53 is to respond to...

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Detalhes bibliográficos
Main Authors: Suzuki, Kazufumi, Matsubara, Hisahiro
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3134396/
https://ncbi.nlm.nih.gov/pubmed/21765642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/978312
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