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Nuclear receptor SHP inhibition of Dnmt1 expression via ERRγ

We describe a transcriptional mechanism regulating the expression of Dnmt1 by nuclear receptors. We show that ERRγ functions as a transcriptional activator of mouse and human Dnmt1 expression by direct binding to its response elements (ERE1/ERE2) in the dnmt1/DNMT1 promoters. The induction of Dnmt1...

詳細記述

保存先:
書誌詳細
主要な著者: Zhang, Yuxia, Wang, Li
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3134389/
https://ncbi.nlm.nih.gov/pubmed/21459093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2011.03.059
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