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Nuclear receptor SHP inhibition of Dnmt1 expression via ERRγ
We describe a transcriptional mechanism regulating the expression of Dnmt1 by nuclear receptors. We show that ERRγ functions as a transcriptional activator of mouse and human Dnmt1 expression by direct binding to its response elements (ERE1/ERE2) in the dnmt1/DNMT1 promoters. The induction of Dnmt1...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3134389/ https://ncbi.nlm.nih.gov/pubmed/21459093 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2011.03.059 |
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