Evaluation of Plaque Stability of Advanced Atherosclerotic Lesions in Apo E-Deficient Mice after Treatment with the Oral Factor Xa Inhibitor Rivaroxaban

Aim. Thrombin not only plays a central role in thrombus formation and platelet activation, but also in induction of inflammatory processes. Activated factor X (FXa) is traditionally known as an important player in the coagulation cascade responsible for thrombin generation. We assessed the hypothesi...

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Main Authors: Zhou, Qianxing, Bea, Florian, Preusch, Michael, Wang, Hongjie, Isermann, Berend, Shahzad, Khurrum, Katus, Hugo A., Blessing, Erwin
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2011
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3134269/
https://ncbi.nlm.nih.gov/pubmed/21772662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/432080
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