Integrative analysis of gene amplification in Drosophila follicle cells: parameters of origin activation and repression

In metazoans, how replication origins are specified and subsequently activated is not well understood. Drosophila amplicons in follicle cells (DAFCs) are genomic regions that undergo rereplication to increase DNA copy number. We identified all DAFCs by comparative genomic hybridization, uncovering t...

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Autores principales: Kim, Jane C., Nordman, Jared, Xie, Fang, Kashevsky, Helena, Eng, Thomas, Li, Sharon, MacAlpine, David M., Orr-Weaver, Terry L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2011
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Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3134082/
https://ncbi.nlm.nih.gov/pubmed/21724831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.2043111
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