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Parathyroid tumor development involves deregulation of homeobox genes

Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant syndrome caused by mutations in the MEN1 tumor suppressor gene. Loss of the functional second copy of the MEN1 gene causes individuals to develop multiple endocrine tumors, primarily affecting the parathyroid, pituitary, and pancrea...

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Detalhes bibliográficos
Main Authors: Shen, H-C Jennifer, Rosen, Jennifer E, Yang, Lauren M, Savage, Sharon A, Burns, A Lee, Mateo, Carmen M, Agarwal, Sunita K, Chandrasekharappa, Settara C, Spiegel, Allen M, Collins, Francis S, Marx, Stephen J, Libutti, Steven K
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133970/
https://ncbi.nlm.nih.gov/pubmed/18310293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/ERC-07-0191
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