The tumor suppressor protein menin inhibits AKT activation by regulating its cellular localization

Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder associated mainly with tumors of multiple endocrine organs. Mutations in the MEN1 gene that encodes for the menin protein are the predominant cause for hereditary MEN1 syndrome. Though menin is a tumor suppressor, its molec...

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Detaylı Bibliyografya
Asıl Yazarlar: Wang, Yan, Ozawa, Atsushi, Zaman, Shadia, Prasad, Nijaguna B., Chandrasekharappa, Settara C., Agarwal, Sunita K., Marx, Stephen J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076053/
https://ncbi.nlm.nih.gov/pubmed/21127195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-3221
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