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In vitro Hematopoietic Differentiation of Mouse Embryonic Stem Cells Requires the Tumor Suppressor Menin and is Mediated by Hoxa9

Inactivating mutations in the tumor suppressor gene MEN1 cause the inherited cancer syndrome multiple endocrine neoplasia type 1 (MEN1). The ubiquitously expressed MEN1 encoded protein, menin, interacts with MLL (mixed-lineage leukemia protein), and together they are essential components of a multip...

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書誌詳細
主要な著者: Novotny, Elizabeth, Compton, Sheila, Liu, P. Paul, Collins, Francis S., Chandrasekharappa, Settara C.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2717021/
https://ncbi.nlm.nih.gov/pubmed/19393316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mod.2009.04.001
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