In vitro Hematopoietic Differentiation of Mouse Embryonic Stem Cells Requires the Tumor Suppressor Menin and is Mediated by Hoxa9

Inactivating mutations in the tumor suppressor gene MEN1 cause the inherited cancer syndrome multiple endocrine neoplasia type 1 (MEN1). The ubiquitously expressed MEN1 encoded protein, menin, interacts with MLL (mixed-lineage leukemia protein), and together they are essential components of a multip...

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Главные авторы: Novotny, Elizabeth, Compton, Sheila, Liu, P. Paul, Collins, Francis S., Chandrasekharappa, Settara C.
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2717021/
https://ncbi.nlm.nih.gov/pubmed/19393316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mod.2009.04.001
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