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Bortezomib Treatment to Potentiate the Anti-tumor Immunity of Ex-vivo Expanded Adoptively Infused Autologous Natural Killer Cells

Our results show that using an EBV-LCL feeder cell line, large numbers of pure populations of highly activated NK cells can be expanded ex vivo under GMP conditions. With the exception of thyroiditis and constitutional symptoms related to IL-2 therapy, infusions of up to 1 x 10(8) cells/kg of ex viv...

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Bibliografiske detaljer
Main Authors: Lundqvist, Andreas, Berg, Maria, Smith, Aleah, Childs, Richard W.
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133963/
https://ncbi.nlm.nih.gov/pubmed/21750690
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