Regulation of thyroid hormone activation via the liver X-receptor/retinoid X-receptor pathway

Thyroid hormone receptor (TR) and liver X-receptor (LXR) are the master regulators of lipid metabolism. Remarkably, a mouse with a targeted deletion of both LXRα and LXRβ is resistant to western diet-induced obesity, and exhibits ectopic liver expression of the thyroid hormone activating type 2 deio...

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Bibliografiske detaljer
Main Authors: Christoffolete, Marcelo A, Doleschall, Márton, Egri, Péter, Liposits, Zsolt, Zavacki, Ann Marie, Bianco, Antonio C, Gereben, Balázs
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133926/
https://ncbi.nlm.nih.gov/pubmed/20176747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/JOE-09-0448
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