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Regulation of thyroid hormone activation via the liver X-receptor/retinoid X-receptor pathway
Thyroid hormone receptor (TR) and liver X-receptor (LXR) are the master regulators of lipid metabolism. Remarkably, a mouse with a targeted deletion of both LXRα and LXRβ is resistant to western diet-induced obesity, and exhibits ectopic liver expression of the thyroid hormone activating type 2 deio...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3133926/ https://ncbi.nlm.nih.gov/pubmed/20176747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/JOE-09-0448 |
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